Asiaticoside (CAS 16830-15-2) is a natural triterpenoid saponin derived from Centella asiatica (gotu kola) widely used in medicine and cosmetics for its significant wound-healing, anti-inflammatory, and antioxidant properties. It accelerates skin repair, boosts collagen synthesis, and acts as an anti-fibrotic agent for scar reduction.

• Appearance: White to off-white powder, slightly bitter taste.
• Formula: C48H78O19.
• Structure: It is a trisaccharide derivative of asiatic acid, comprising a sugar moiety linked to a triterpenoid.
• Solubility: Higher solubility in polar solvents; soluble in DMF (25mg/ml), DMSO (10mg/ml), ethanol (5mg/ml), and PBS (10mg/ml).
• Source: Extracted from Centella asiatica (Gotu Kola).

• Wound Healing & Scar Reduction: Promotes epithelialization, stimulates collagen synthesis, and increases hydroxyproline content, which improves tensile strength in skin repair.
• Anti-inflammatory: Suppresses inflammatory cytokines (TNF-alpha, IL-1 beta, IL-6) and inhibits the NF-kB signaling pathway.
• Antioxidant: Neutralizes free radicals and reduces oxidative stress.
• Anti-fibrotic/Anti-keloid: Inhibits keloid fibroblast proliferation and reduces TGF-beta/Smad signaling.
• Neuroprotective: Supports neuronal health, promotes stem cell growth, and enhances cognitive function.

• Medicine: Used for treating wounds, burns, skin disorders (dermatitis), chronic venous insufficiency, and keloidal scars.
• Cosmetics/Skincare: Integrated into anti-aging and skin-repair products to enhance elasticity and collagen density.
• Research: Studied for potential anti-tumor effects (melanoma, breast cancer) and neurological benefits.
• Recommended Storage: Store at +4℃ to maintain stability.